After decades of investigations into the so-called Highway of Tears murders, RCMP may be set to reveal some answers Tuesday. And on Wednesday, investigators will be Kamloops to speak with media.

Representatives from a joint investigation team called Project E-PANA are holding a press conference Tuesday to announce "significant developments" into the investigation into 18 women who went missing or were murdered along B.C. highways 16, 5, 1 and 97 between 1969 and 2006.

"Police will also be issuing a plea for assistance from British Columbians, Canadians and Americans," states a press release.

The representatives include B.C. RCMP, officials from the U.S., a victim family member and investigators with Project E-PANA, which was established in 2006 to investigate 18 cases of missing and murdered women.

It's unclear what, if any, connection investigators have made to Kamloops. But Kamloops does figure in the tragic history of murders.

Two women on the police's Highway of Tears list were linked to Kamloops.

On Nov. 6, 1973, 19-year-old Pamela Darlington was last seen in Kamloops. She was believed to be hitchhiking. Her body was found on the front yard of a house near Riverside Park.

And on May 8, 1981, 33-year-old Maureen Mosie was last seen in Salmon Arm. She was reportedly trying to hitchhike to Kamloops but never made it. Her body was found May 9, 1981 at the end of a run-off lane on Highway 97 near the Trans-Canada highway, about 16 km east of Kamloops.

Also on the Highway of Tears list is 12-year-old Monica Jack of Merritt who died in 1978. Jack disappeared while out riding her bike near a lakeside road. Her bones were found in February 1996.

Kamloops RCMP investigator Mike Eastman was consumed with trying to solve the case, according to archived media reports.

In 1981, he organized a conference to compare notes on the growing number of unsolved female homicides along highways in the Interior of B.C. and into Alberta. More than 40 investigators attended.

But no suspect was ever charged.